The second round draw for the Barry Cup is as follows –
• AFC Rhoose vs Vale United
• St Athan vs Vale Athletic
• Vale Madrid vs Cardiff Airport
• Island Marine vs Rhoose Social
• BV vs Cogan Coronation
• Sully Sports vs Tynewydd
• Penarth Town vs Holton Road
• Barry Athletic receive a bye to the next round (due to the withdrawal of Cadoxton Barry)
Ties to be played on 8th October 2022.